MUC1 (Mucin 1)

  • Used for: Breast cancer, ovarian cancer, pancreatic cancer.
  • Why it’s good: Overexpression of MUC1 is seen in many cancers, making it a broad biomarker.
  • Limitation: It can be elevated in non-cancerous conditions as well.

Similar Posts

Alpha-Fetoprotein (AFP)

AFP (Alpha-Fetoprotein)

Byadmin

Alpha-Fetoprotein (AFP) is a well-established cancer biomarker with diverse clinical applications, especially in liver and germ cell tumors. Here’s a detailed summary of its biological role, diagnostic value, prognostic utility, and emerging therapeutic applications, based on recent studies: 🔬 What is AFP? AFP is a glycoprotein produced by the fetal liver and yolk sac. After…

Carcinoembryonic Antigen (CEA)

CEA (Carcinoembryonic Antigen)

Byadmin

CEA is a cell adhesion molecule normally produced during fetal development. In adults, it is usually undetectable in the blood, but it may be re-expressed and elevated in certain cancers, including colorectal, gastric, pancreatic, breast, and lung cancers (Vrba et al., 1975). 🧪 Diagnostic Applications 📈 Prognostic Value 🧪 CEA in Non-Gastrointestinal Cancers 🧪 CEA…

KRAS mutations

KRAS Mutations

Byadmin

KRAS mutations are among the most common oncogenic drivers in human cancers, notably in pancreatic, colorectal, and lung cancers. The KRAS gene encodes a protein that functions as a molecular switch, regulating cell growth and division. Mutations, particularly at codon 12 (such as G12D), impair the protein’s GTPase activity, leading to uncontrolled cellular proliferation. KRAS…